The development from the gRNA dimer is mediated by a 'kissing' interaction in between the DIS hairpin loops of the gRNA monomers. At the same time, selected guanosine residues in the gRNA are created readily available for binding of the nucleocapsid (NC) protein bringing about the subsequent virion assembly.[seventy one] https://hivhub.in/hiv-epidemic-in-india-trends-and-state-wise-distribution/